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Marco Leo, Pierluigi Carcagnì, Luca Signore, Francesco Corcione, Giulio Benincasa, Mikko O. Laukkanen and Cosimo Distante
Colorectal cancer is one of the most lethal cancers because of late diagnosis and challenges in the selection of therapy options. The histopathological diagnosis of colon adenocarcinoma is hindered by poor reproducibility and a lack of standard examinati...
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Rejane Viana, Ana C. Rocha, André P. Sousa, Diogo Ferreira, Rúben Fernandes, Cátia Almeida, Patrick J. Pais, Pilar Baylina and Ana Cláudia Pereira
Colorectal cancer (CRC) is the third most common cancer diagnosed today and the third leading cause of death among cancer types. CRC is one of the gastrointestinal tumors with obesity as the main extrinsic risk factor, since, according to authors, the me...
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Cosimo Cardellicchio, Valentino Laquintana, Rosa Maria Iacobazzi, Nunzio Denora, Antonio Scilimati, Maria Grazia Perrone and Maria Annunziata M. Capozzi
Sulindac is a well-known anti-inflammatory agent, sometimes employed as an adjuvant in antitumor therapy. Due to the recent interest in sulfoximine for its potential chemotherapeutics, we decided to transform sulindac and its methyl ester into the corres...
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Kaliyamoorthy Kalidasan, Laurent Dufossé, Gunasekaran Manivel, Poomalai Senthilraja and Kandasamy Kathiresan
This work studied the antioxidant and anti-colorectal cancer properties of a potential strain of thraustochytrids, Schizochytrium sp. (SMKK1), isolated from mangrove leaf litter. The biomass was extracted with methanol and screened for antioxidant activi...
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Sergey A. Soldatov, Danil M. Pashkov, Sergey A. Guda, Nikolay S. Karnaukhov, Alexander A. Guda and Alexander V. Soldatov
Microscopic tissue analysis is the key diagnostic method needed for disease identification and choosing the best treatment regimen. According to the Global Cancer Observatory, approximately two million people are diagnosed with colorectal cancer each yea...
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Kicheol Yoon, Jun-Won Chung and Kwang Gi Kim
In laparoscopic surgery for colorectal and gastric cancer, it is difficult to locate the tumor in the cavity for excision. Tumors in the colon or stomach are blocked by mucous membranes; thus, the view from the cavity is obscured. Therefore, to determine...
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Mukul Kumar, Deepika Kaushik, Jasjit Kaur, Charalampos Proestos, Fatih Oz, Emel Oz, Prerna Gupta, Priyanka Kundu, Anmol Kaur, Anisha Anisha and Ritika Ritika
Obesity is arising as a global pandemic throughout the world. Over the past few decades, obesity has tripled worldwide, creating an alarming situation. The majority of people nowadays are suffering from obesity and overweight. It affects health of people...
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Athanasios Kallipolitis, Kyriakos Revelos and Ilias Maglogiannis
The extended utilization of digitized Whole Slide Images is transforming the workflow of traditional clinical histopathology to the digital era. The ongoing transformation has demonstrated major potentials towards the exploitation of Machine Learning and...
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Mukta Sharma, Venkanagouda S. Goudar, Manohar Prasad Koduri, Fan Gang Tseng and Mahua Bhattacharya
This work proposes a novel region-estimation (RE) algorithm using the quantification of colon-cancer (HCT-8) and fibroblasts (NIH3T3) cells to estimate the densest region of colon-cancer cells in in vitro 3D co-cultured spheroids. Cells were labelled wit...
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Perla Yolanda López-Camacho, Juan Carlos Martínez-Espinosa, Gustavo Basurto-Islas, Andrea Torres-Zarraga, José Martín Márquez-Villa, Mariana Macías-Alonso and Joaquin G. Marrero
Spondias mombin L. has been used in traditional medicine to treat some cases such as infections and inflammations. Some researchers have reported that its biological components, such as carotenoids, carotenes, and phenols, have been characterized primari...
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