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Elliasu Y. Salifu, Mbuso A. Faya, James Abugri and Pritika Ramharack
Cancer remains a major challenge in the field of medicine, necessitating innovative therapeutic strategies. Mitogen-activated protein kinase (MAPK) signaling pathways, particularly Extracellular Signal-Regulated Kinase 1 and 2 (ERK1/2), play pivotal role...
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Chieh Lun Liu, Erica A. Dasi, Aaron M. Watson, Allen R. Place and Rosemary Jagus
The present study investigates the response of the marine fish cobia, Rachycentron canadum, to stressors as measured by phosphorylation of the a-subunit of the translational initiation factor, eIF2. eIF2a is the target of phosphorylation by a family of k...
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Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi and Carmela Saturnino
The carbazole class is made up of heterocyclically structured compounds first isolated from coal tar. Their structural motif is preponderant in different synthetic materials and naturally occurring alkaloids extracted from the taxonomically related highe...
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Thanasekaran Jayakumar, Ming-Ping Wu, Joen-Rong Sheu, Chih-Wei Hsia, Periyakali Saravana Bhavan, Manjunath Manubolu, Chi-Li Chung and Chih-Hsuan Hsia
Pterostilbene (PTE), a natural stilbenoid occurring in grapes and berries, is recognized as a dimethylated analogue of resveratrol. This compound shows numerous notable pharmacological activities, including antiaging, anticancer, antidiabetes, antioxidan...
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Chih-Wei Hsia, Chih-Hao Yang, Joen-Rong Sheu, Chih-Hsuan Hsia, Cheng-Lin Tsai, Wei-Chieh Huang, Ting-Yu Chen, Thanasekaran Jayakumar, Periyakali Saravana Bhavan and Yi Chang
Myocardial infarction and cerebral ischemic stroke during the process of arterial thrombosis are prominently causes of death worldwide. Platelets are anucleated cells and play a critical factor in these diseases. Columbianadin (CBN), a coumarin derivativ...
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Thomas Makungo, Tsepo Tsekoa, Anjo Theron, Dalu Mancama, Teunis van Ree
Met die toenemende voorkoms van weerstandige Plasmodium stamme het die beheer van malaria-voorkoms en -mortaliteit weer op die voorgrond getree. Nuwe teikens en antimalariamiddels wat effektief is teen weerstandige malaria-parasiete word dus dr...
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Robert Siblerud, Joachim Mutter, Elaine Moore, Johannes Naumann and Harald Walach
Mercury is one of the most toxic elements and causes a multitude of health problems. It is ten times more toxic to neurons than lead. This study was created to determine if mercury could be causing Alzheimer?s disease (AD) by cross referencing the effect...
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René Viñas, Yow-Jiun Jeng and Cheryl S. Watson
Xenoestrogens (XEs) are chemicals derived from a variety of natural and anthropogenic sources that can interfere with endogenous estrogens by either mimicking or blocking their responses via non-genomic and/or genomic signaling mechanisms. Disruption of ...
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