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Hiroshi Yamazaki, Kana Horiuchi, Ryohji Takano, Taku Nagano, Makiko Shimizu, Masato Kitajima, Norie Murayama and Fumiaki Shono
The present study defined a simplified physiologically based pharmacokinetic (PBPK) model for nicotine and its primary metabolite cotinine in humans, based on metabolic parameters determined in vitro using relevant liver microsomes, coefficients derived ...
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Taku Nagano, Makiko Shimizu, Kazuma Kiyotani, Tetsuya Kamataki, Ryohji Takano, Norie Murayama, Fumiaki Shono and Hiroshi Yamazaki
Human biomonitoring of plasma and urinary levels of nicotine, cotinine, and 3'-hydroxycotinine was conducted after daily cigarette smoking in a population of 92 male Japanese smokers with a mean age of 37 years who had smoked an average of 23 cigarettes ...
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Takashi Ikeda, Keisuke Yamazaki, Hiroshi Kumakura, and Hiroshi Hamamoto
Pág. 88 - 90
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Tsutomu Aida, Ai Yamazaki, Makoto Akutsu, Takumi Ono, Akihiro Kanno, Taka-aki Hoshina, Masaki Ota, Masaru Watanabe, Yoshiyuki Sato, Richard L. Smith, Jr., and Hiroshi Inomata
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Minoru YAMAZAKI, Yukinobu NATSUME, Hiroshi HARADA and Kenichi OHSAS
Pág. 903
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