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Meynard Austria, Jon Patrick Garcia, Alvin Caparanga, Lemmuel Tayo and Bonifacio Doma, Jr.
Polymerase chain reaction (PCR) technique is one of the molecular methods in amplifying DNA for the detection of malaria. However, the collection and transportation of samples and the processing and dissemination of results via conventional PCR, especial...
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Sara Lledó Villaescusa and Rafael Lahoz-Beltra
At present, synthetic biology applications are based on the programming of synthetic bacteria with custom-designed genetic circuits through the application of a top-down strategy. These genetic circuits are the programs that implement a certain algorithm...
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Yuko Terada, Kenjiro Tanaka, Minami Matsuyama, Masaya Fujitani, Masatoshi Shibuya, Yoshihiko Yamamoto, Ryuji Kato and Keisuke Ito
Because transient receptor potential ankyrin 1 (TRPA1) is involved in various physiological functions, TRPA1-targeting drugs have been energetically developed. Although TRPA1 is considered a multimodal receptor, the structural diversity of TRPA1 agonists...
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Eftichia Kritsi, Thalia Tsiaka, Alexandros-George Ioannou, Vassiliki Mantanika, Irini F. Strati, Irene Panderi, Panagiotis Zoumpoulakis and Vassilia J. Sinanoglou
The incorporation of edible flowers in the human diet and culinary preparations dates back to ancient times. Nowadays, edible flowers have gained great attention due to their health-promoting and nutritive effects and their widespread acceptance by consu...
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Woo-Suck Han, Jérôme Molimard, Baptiste Pierrat, Romain Pannetier and Reynald Convert
A comparative study of eight different lumbar belts, which are representative of the French market, was carried out on four typical morphologies of patients to assess their therapeutic effects and identify the correlation between the therapeutic paramete...
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Diego Armando Maldonado-Torres, D. Alejandro Fernández-Velasco, Gema Morales-Olán, Flor de Fátima Rosas-Cárdenas and Silvia Luna-Suárez
This work introduces a novel way of designing proteins for the treatment of diseases, especially metabolic syndrome.
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Dragos Paul Mihai, Cosmin Trif, Gheorghe Stancov, Denise Radulescu and George Mihai Nitulescu
Transient receptor potential ankyrin 1 (TRPA1) is a ligand-gated calcium channel activated by cold temperatures and by a plethora of electrophilic environmental irritants (allicin, acrolein, mustard-oil) and endogenously oxidized lipids (15-deoxy-?12, 14...
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Hendrikje Raben, Peer W. Kämmerer, Rainer Bader and Ursula van Rienen
Electrical stimulation is a promising therapeutic approach for the regeneration of large bone defects. Innovative electrically stimulating implants for critical size defects in the lower jaw are under development and need to be optimized in silico and te...
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Nicole Lazzeri, Daniele Mazzei, Lorenzo Cominelli, Antonio Cisternino and Danilo Emilio De Rossi
Humans have an innate tendency to anthropomorphize surrounding entities and have always been fascinated by the creation of machines endowed with human-inspired capabilities and traits. In the last few decades, this has become a reality with enormous adva...
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Yana A. Sharapova,Dmitry A. Suplatov,Vytas K. ?vedas
Pág. 30 - 33
Understanding the conformational dynamics which affects ligand binding by Neuraminidases is needed to improve the in silico selection of novel drug candidates targeting these pathogenicity factors and to adequately estimate the efficacy of potential drug...
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