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Artur Chudzik and Andrzej W. Przybyszewski
Neurodegenerative diseases (NDs), including Parkinson?s and Alzheimer?s disease, pose a significant challenge to global health, and early detection tools are crucial for effective intervention. The adaptation of online screening forms and machine learnin...
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Cristina Ramona Novaconi, Robert Onulov, Alina Florina Serb, Eugen Sisu, Nicolae Dinca, Mihai-Cosmin Pascariu and Marius Georgescu
Glycosphingolipids (GSLs) are a glycolipid subtype which plays vital roles in numerous biological processes, cell?cell interactions, as well as oncogenesis and ontogenesis. They are ubiquitous molecules found mostly in cell membranes. Abnormal expression...
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Zhaoyi Chen, Yuchen Yang, Dazheng Zhang, Jingchuan Guo, Yi Guo, Xia Hu, Yong Chen and Jiang Bian
Alzheimer?s disease (AD) and AD-related dementias (AD/ADRD) are a group of progressive neurodegenerative diseases. The progression of AD can be conceptualized as a continuum in which patients progress from normal cognition to preclinical AD (i.e., no sym...
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Jingeun Kim, Hye-Jin Park and Yourim Yoon
Parkinson?s disease is a neurodegenerative disease that is associated with genetic and environmental factors. However, the genes causing this degeneration have not been determined, and no reported cure exists for this disease. Recently, studies have been...
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Maria Dyah Nur Meinita, Dicky Harwanto and Jae-Suk Choi
Seaweeds or marine macroalgae are known for producing potentially bioactive substances that exhibit a wide range of nutritional, therapeutic, and nutraceutical properties. These compounds can be applied to treat chronic diseases, such as cancer, cardiova...
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Alberto J. Nuñez-Selles, Lauro Nuevas-Paz and Gregorio Martínez-Sánchez
Metal?mangiferin complexes as antioxidant and protecting agents against protein oxidative damage in adjuvant therapies of pathologies of high morbidity and mortality: neurodegenerative diseases, cancer, diabetes, and cardiovascular disorders.
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Dina Zidan and Azrina Azlan
Non-centrifugal sugar (NCS) is the scientific term the Food and Agriculture Organization (FAO) uses to define a solid product, produced by sugarcane juice evaporation, which is unrefined or minimally refined. NCS is referred to in various names globally,...
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Min Hye Kang, Yun-Jeong Ji, Yu Mi Han, Gwi Yeong Jang, Dong Hwi Kim, Jeong Hoon Lee, Geum-Soog Kim, Su Ji Choi and Hyung Don Kim
The overproduction of reactive oxygen species (ROS) can cause oxidative stress to biomolecules such as nucleic acids, proteins, and lipids, leading to neurodegenerative disorders. Sasa borealis (SB) has antioxidant, anti-inflammatory, antidiabetic, and a...
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Lucía Soliño, Sea-Yong Kim, Alfredo López, Pablo Covelo, Sara Rydberg, Pedro Reis Costa and Sandra Lage
The neurotoxin ß-N-methylamino-L-alanine (BMAA), a non-proteinogenic amino acid produced by several species of both prokaryotic (cyanobacteria) and eukaryotic (diatoms) microorganisms, has been proposed to be associated with the development of neurodegen...
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Haya I. Aljohar, Abdulmajeed A. Alghamdi, Nasr Y. Khalil, Hany W. Darwish, Rashad Al-Salahi and Ibrahim A. Darwish
The Food and Drug Administration (FDA) has approved duvelisib (DUV) for managing follicular lymphoma, small lymphocytic lymphoma, and relapsed or refractory chronic lymphocytic leukemia. Seliciclib (SEL) is a candidate drug for these cancers, neurodegene...
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