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Adina Pop Moldovan, Simona Dumitra, Cristina Popescu, Radu Lala, Nicoleta Zurbau Anghel, Daniel Nisulescu, Ariana Nicoras, Coralia Cotoraci, Monica Puticiu, Anca Hermenean and Daniela Teodora Marti
Anthracyclines, including epirubicin (Epi), are effective chemotherapeutics but are known for their cardiotoxic side effects, primarily inducing cardiomyocyte apoptosis. This study investigates the protective role of hesperetin (HSP) against cardiomyopat...
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Jinnatun Nahar, Vinothini Boopathi, Esrat Jahan Rupa, Muhammad Awais, Anjali Kariyarath Valappil, Md Niaj Morshed, Mohanapriya Murugesan, Reshmi Akter, Dong Uk Yang, Ramya Mathiyalagan, Deok Chun Yang and Seok-Kyu Jung
The family Thymelaeaceae, which includes huge evergreen trees that are sparsely distributed in tropical rainforests, includes the genus Aquilaria. Numerous medical conditions, including inflammation, cancer, and oxidative stress have been traditionally t...
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Hao Zhu, Wendi Cao, Yicai Huang, Niel A. Karrow and Zhangping Yang
Pyocyanin (PCN) is an extracellular toxin secreted by Pseudomonas aeruginosa (PA), which has redox capacity and disrupts the redox balance of host cells, affecting cell function and leading to cell death. The aim of this experiment was to compare the deg...
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Nazia Afroze, Sreepoorna Pramodh, Abdulmajeed G. Almutary, Tahir A. Rizvi, Naushad Rais, Ritu Raina, Md. Faiyazuddin, Abdullah M. Alnuqaydan and Arif Hussain
Kaempferol, a flavonoid, contains a plethora of therapeutic properties and has demonstrated its efficacy against cancer. This study aims to unravel the molecular targets that are being modulated by kaempferol on HeLa cells. Various assays were performed,...
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Thanh Quang Nguyen, Hoang Nhat Minh Nguyen, Dai-Hung Ngo, Phuoc-Hien Phan and Thanh Sang Vo
Epidemiological studies have evidenced that natural dietary products can prevent or manage gastric cancer. Neptunia oleracea, an aquatic vegetable and edible plant, has been reported to have anti-cancer properties. In this study, N. oleracea extract?s su...
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Saleh A. Almatroodi, Amjad Ali Khan, Abdulaziz A. Aloliqi, Mansoor Ali Syed and Arshad Husain Rahmani
Chronic respiratory diseases are a leading cause of lung-related death worldwide. The vital factors causing lung pathogenesis include consistent exposure to tobacco smoke, air pollution, and occupational risks. Regarding the significant morbidity and mor...
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Abdulaziz A. Al-Khedhairy and Rizwan Wahab
The size of nanomaterials influences physicochemical parameters, and variations in the size of nanomaterials can have a significant effect on their biological activities in cells. Due to the potential applicability of nanoparticles (NPs), the current wor...
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Hae-Jin Lee, Hae-Lim Kim, Dae-Young Lee, Dong-Ryung Lee, Bong-Keun Choi and Seung-Hwan Yang
We evaluated the effectiveness of Scrophularia buergeriana extract (Brainon) on cognitive dysfunction and determined its underlying mechanisms in a scopolamine (SCO)-treated mouse model of memory impairment. Brainon treatment for 28 days ameliorated the ...
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Yoonjin Park, Gyeong Hee Shin, Gyo Sik Jin, Sungbae Jin, Boyong Kim and Seung Gwan Lee
Jade, a popular gemstone symbolizing beauty, grace, and longevity, is known to improve blood circulation; however, scientific research evidence is still lacking. The effect of black jade extract on the expression levels of apoptotic and osteogenic genes ...
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Coralia Cotoraci, Alciona Sasu, Eftimie Miutescu, Dana Iovanescu, Sami Gharbia, Alina Ciceu, Hildegard Herman and Anca Hermenean
Chemotherapy and radiation are often accompanied by complications such as intestinal mucositis. The aim of this study was to assess by immunohistochemical assay the consequences of epirubicin-based therapy applied to onco-hematological patients, on the m...
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