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Carla S. S. Ferreira, Miguel Oliveira, Mário Pacheco and Maria Ana Santos
The physiological conditions of an organism may influence its ability to cope with environmental stressors, such as contaminants. Biotransformation and the endocrine system interact with each other to promote animal?s fitness. However, little is known re...
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Kangxuan Chen, Shihao Li, Jianhai Xiang, Amir Sagi and Fuhua Li
The insulin-like androgenic gland hormone (IAG) plays a key role in male sexual differentiation and spermatogenesis in crustaceans. The expression of IAG is usually negatively regulated by neuropeptide hormones through the ?eyestalk-AG? endocrine axis. H...
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Yuanyuan Li, Jia Guo, Shoulong Deng, Zili Gao, Yixun Liu and Qi Gu
Polycystic ovarian syndrome (PCOS) is a ubiquitous hormonal disorder and induces female infertility and heterogeneous syndromes, for which there is still no effective treatment. Thanks to the properties of immunomodulatory and endocrine regulation, mesen...
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Ernesto Burgio, Prisco Piscitelli and Annamaria Colao
The dominant pathogenic model, somatic mutation theory (SMT), considers carcinogenesis as a ?genetic accident? due to the accumulation of ?stochastic? DNA mutations. This model was proposed and accepted by the scientific community when cancer mainly affe...
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Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden and David B. Allison
Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999?2002), we investigated the association between body mass index (BMI...
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