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Nazia Ejaz, Saad Jawaid Khan, Fahad Azim, Mehwish Faiz, Emil Teu?an, Alin Ple?a, Alexandru Ianosi-Andreeva-Dimitrova and Sergiu-Dan Stan
Fragility fractures, caused by low-energy trauma, are a significant global health concern, with 158 million people aged 50 and over at risk. Hip fractures, a common issue in elderly patients, are often linked to underlying conditions such as osteoporosis...
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Harold Dadomo, Davide Ponzi, Silvia Paterlini, Stefano Parmigiani and Paola Palanza
Age-dependent cognitive decline is associated with a downregulation of the cyclic nucleotide cascade. Through their regulation of the cGMP pathway, phosphodiesterase 5 inhibitors have been proven to enhance episodic memory in rodents and mice and have be...
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Naghmeh Jafarpournaser, Mahmoud Reza Delavar and Maryam Noroozian
The increasing prevalence of cognitive disorders among the elderly is a significant consequence of the global aging phenomenon. Wandering stands out as the most prominent and challenging symptom in these patients, with potential irreversible consequences...
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Denise M. T. Yu, Stephanie Dauth, Michael B. Margineanu, Valentina Snetkova, Maren Rehders, Silvia Jordans and Klaudia Brix
Endolysosomal cathepsin expression and activities are differentially regulated in the cortex, striatum, hippocampus, and cerebellum of mice upon aging and/or cathepsin deficiencies.
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