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Michele Basilicata, Giulia Marrone, Manuela Di Lauro, Eleonora Sargentini, Vincenza Paolino, Redan Hassan, Giuseppe D?Amato, Patrizio Bollero and Annalisa Noce
Gaucher disease (GD) is a lysosomal storage pathological condition, characterized by a genetic autosomal recessive transmission. The GD cause is the mutation of GBA1 gene, located on the chromosome 1 (1q21), that induces the deficiency of the lysosomal e...
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Lei Cao, Won Han, Sang Gil Lee and Joong Ho Shin
Cell-culture-based drug tests are usually performed in an instantaneous delivery manner. However, in vivo pharmacokinetic studies have shown a steady increase in the concentration of bioactive compounds in the plasma following oral administration, with t...
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Yong-Han Hong, Chieh Kao, Chi-Chang Chang, Fu-Kuei Chang, Tuzz-Ying Song, Jer-Yiing Houng and Chi-Hao Wu
Banana peel (BP) has potent antioxidative properties; however, the anti-inflammatory potential of BP and its related bioactive components remain unclear. This study used solvent extraction and gas chromatography?mass spectrometry (GC?MS) to isolate and i...
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Layla Panahipour, Anes Omerbasic, Azarakhsh Oladzad Abbasabadi, Jila Nasirzade, Zahra Kargarpour and Reinhard Gruber
Demineralized bone matrix (DBM) is commonly used for the reconstruction of bone defects. Early graft consolidation involves a transient inflammatory process. It is, however, unclear whether DBM can modulate this process. To test this possibility, we prep...
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Po-Tsang Lee, Yu-Sheng Wu, Chung-Chih Tseng, Jia-Yu Lu and Meng-Chou Lee
This study evaluated the effects of the feeding of spent mushroom substrate from Agaricus blazei on Nile tilapia (Oreochromis niloticus). The safety of 0?1000 µg/mL A. blazei spent substrate water extract (ABSSE) was demonstrated in the primary hepatic a...
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Ju-Hui Kim, Ji-Su Kim, Si-Hyun Kim, Su-Hyeon Jeong, Un-Yul Jeong, Ji-Eun Jung, Sun-Kyung Lee and Sung-Hyen Lee
This study was conducted to evaluate and to increase the usage of the whole onion (Allium cepa L.), which is composed of a small bulb and many leaves that are discarded as by-products before the bulbs grow. Whole onions are harvested early in immature co...
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Po-Kai Pan, Tsung-Meng Wu, Chiu-Ming Wen, Yin-Yu Chen and Yu-Sheng Wu
Sarcodia suieae acetyl-xylogalactan was reported to induce macrophage polarisation, and could positively regulate macrophage activation. In this study, we evaluated the effect of Sarcodia suieae acetyl-xylogalactan on the Nile tilapia. First, we assessed...
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Ye-Eun Choi, Jung-Mo Yang and Ju-Hyun Cho
Owing to global population aging, instances of bone metabolic diseases have increased. Consequently, interest in natural and functional plant food products for the prevention and treatment of osteoporosis is also increasing. In this study, we determine t...
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Pugar Arga Cristina Wulandari, Zulfa Nailul Ilmi, Saikhu Akhmad Husen, Dwi Winarni, Mochammad Amin Alamsjah, Khalijah Awang, Marco Vastano, Alessandro Pellis, Duncan MacQuarrie and Pratiwi Pudjiastuti
A diabetic foot ulcer is an open wound that can become sore and frequently occurs in diabetic patients. Alginate has the ability to form a hydrophilic gel when in contact with a wound surface in diabetic patients. Xanthones are the main compounds of mang...
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Nicola Gaetano Gatta, Andrea Parente, Francesca Guida, Sabatino Maione and Vittorio Gentile
Background: Tissue type 2 transglutaminase (TG2, E.C. 2.3.2,13) is reported to be involved in the phagocytosis of apoptotic cells in mouse microglial BV2 cells and peripheral macrophages. In this study, by using lipopolysaccharide (LPS)- or amyloid-ß 1-4...
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