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Victoria Pulido-Escribano, Bárbara Torrecillas-Baena, Gabriel Dorado, María Ángeles Gálvez-Moreno, Marta Camacho-Cardenosa and Antonio Casado-Díaz
Hard-to-heal chronic wounds associated with aging and high-prevalence pathologies, such as diabetes, are a global health problem. Therefore, it is necessary to advance effective treatments to accelerate wound healing. Among these potential treatments are...
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Heejin Kim, Ko Eun Lee, Yong Kwon Chae, Ok Hyung Nam, Mi Sun Kim, Ji-Hyun Jang, Sung Chul Choi and Hyo-Seol Lee
The characteristics of 3-dimensional (3D) cultured periodontal ligament stem cells derived from permanent teeth (pPDLSCs) and supernumerary teeth (sPDLSCs) were compared and evaluated in this study. pPDLSCs and sPDLSCs were cultured in an ultra-low attac...
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Anna Maria Sacco, Clotilde Castaldo, Franca Di Meglio, Daria Nurzynska, Stefano Palermi, Rocco Spera, Rossana Gnasso, Giorgio Zinno, Veronica Romano and Immacolata Belviso
Cardiac regeneration is a critical endeavor in the treatment of heart diseases, aimed at repairing and enhancing the structure and function of damaged myocardium. This review offers a comprehensive overview of current advancements and strategies in cardi...
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Boram Son, Seong Ho Lee, Seyoung Hong, Miji Kwon, Jinmyoung Joo, Kwang Suk Lim and Hee Ho Park
Direct reprogramming of somatic cells to myoblasts and myotubes holds great potential for muscle development, disease modeling and regenerative medicine. According to recent studies, direct conversion of fibroblasts to myoblasts was performed by using a ...
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Wiebke Eisler, Manuel Held, Afshin Rahmanian-Schwarz, Jennifer Schiefer, Shahab Rahmanian, Adrien Daigeler and Jan-Ole Baur
The application of exogenous growth factors such as the recombinant human growth and differentiation factor 5 (rhGDF-5) represents a major research topic with great potential for the treatment of complex wounds. In a randomized, controlled minipig study,...
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Neill J. Turner
The present Special Issue comprises a collection of articles addressing the many ways in which extracellular matrix (ECM), or its components parts, can be used in regenerative medicine applications. ECM is a dynamic structure, composed of a three-dimensi...
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Chih-Yu Wu, Yu-Chih Chiang, Jane Christy, Abel Po-Hao Huang, Nai-Yun Chang, Wenny, Yu-Chih Chiu, Yen-Ching Yang, Po-Chun Chen, Peng-Yuan Wang and Hsien-Yeh Chen
Modifications of biomaterials based on the combination of physical, chemical, and biological cues for manipulating stem cell growth are needed for modern regenerative medicine. The exploitation of these sophisticated modifications remains a challenge, in...
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Ricardo Donate, María Elena Alemán-Domínguez, Mario Monzón, Jianshu Yu, Francisco Rodríguez-Esparragón and Chaozong Liu
3D-printed polylactic acid (PLA) scaffolds have been demonstrated as being a promising tool for the development of tissue-engineered replacements of bone. However, this material lacks a suitable surface chemistry to efficiently interact with extracellula...
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Tatyana A. Kuznetsova, Boris G. Andryukov, Natalia N. Besednova, Tatyana S. Zaporozhets and Andrey V. Kalinin
The present review considers the physicochemical and biological properties of polysaccharides (PS) from brown, red, and green algae (alginates, fucoidans, carrageenans, and ulvans) used in the latest technologies of regenerative medicine (tissue engineer...
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Antonella Stanzione, Alessandro Polini, Velia La Pesa, Alessandro Romano, Angelo Quattrini, Giuseppe Gigli, Lorenzo Moroni and Francesca Gervaso
The developed thermoresponsive injectable hydrogels might be used as cell-delivery systems, 3D matrices for cell culture study, drug screening platforms, and for regenerative medicine applications.
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