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Diletta Piatti, Riccardo Marconi, Giovanni Caprioli, Simone Angeloni, Massimo Ricciutelli, Gokhan Zengin, Filippo Maggi, Luca Pagni and Gianni Sagratini
This study assessed the impact of full and late flowering stages on the polyphenols and enzyme inhibitory properties of Hypericum perforatum from Poland. Recognizing the significance of phenolic compounds in disease prevention and melatonin?s emerging pr...
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Young-Joo Yun, Sung-Ah Kim, Jaehee Kim and Jae-Sung Rhee
Diuron, an additive biocide in antifouling paints, is widely employed to curtail the attachment of organisms on submerged surfaces in aquatic structures. Despite the detection of diuron in aquatic ecosystems, information regarding its acute and chronic i...
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Daniela Correia, Inês Domingues, Melissa Faria and Miguel Oliveira
Fluoxetine is an antidepressant widely used to treat depressive and anxiety states. Due to its mode of action in the central nervous system (selective serotonin reuptake inhibitor (SSRI)), it becomes toxic to non-target organisms, leading to changes that...
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Joel B. Johnson, Janice S. Mani and Mani Naiker
Fermented juice from the noni tree (Morinda citrifolia) is a traditional medicinal product used by South Pacific Islanders to treat a wide range of ailments, including cancer, inflammation and obesity, as well as improving overall wellbeing. Many of its ...
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Hae-Jin Lee, Hae-Lim Kim, Dae-Young Lee, Dong-Ryung Lee, Bong-Keun Choi and Seung-Hwan Yang
We evaluated the effectiveness of Scrophularia buergeriana extract (Brainon) on cognitive dysfunction and determined its underlying mechanisms in a scopolamine (SCO)-treated mouse model of memory impairment. Brainon treatment for 28 days ameliorated the ...
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Jiri Kos, Tomas Strharsky, Sarka Stepankova, Katarina Svrckova, Michal Oravec, Jan Hosek, Ales Imramovsky and Josef Jampilek
A series of twelve nature-inspired 3,4,5-trimethoxycinnamates were prepared and characterized. All compounds, including the starting 3,4,5-trimethoxycinnamic acid, were tested for their ability to inhibit acetylcholinesterase (AChE) and butyrylcholineste...
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Azza Silotry Naik, Leticia Mora and Maria Hayes
Functional foods for humans with the potential to prevent diabetes through inhibition of the dipeptidyl peptidase IV (DPP-IV) enzyme.
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Neelam Soni, Vinay Kumar Singh
Pág. 21 - 27
Plants Terminalia arjuna and Tamarindus indica are known to have a significant molluscicidal potential to control the population of vector snails. Since the molluscicides are considered an emerging pollutant and are frequently detected in surface water b...
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Lin Tan, Suxia Guo, Funing Ma, Chen Chang and Isabel Gómez-Betancur
Acetylcholinesterase is one of the most important enzymes in living organisms, which is responsible for the synapse cholinergic and other nervous processes. However, its inhibiting effects have proven to have pharmacological applications in the treatment...
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Sofya V. Lushchekina,Galina F. Makhaeva,Dana A. Novichkova,Irina V. Zueva,Nadezhda V. Kovaleva,Rudy R. Richardson
Pág. 89 - 97
Molecular docking is one of the most popular tools of molecular modeling. However, in certain cases, like development of inhibitors of cholinesterases as therapeutic agents for Alzheimer's disease, there are many aspects, which should be taken into accou...
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