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Michaela Cellina, Maurizio Cè, Marco Alì, Giovanni Irmici, Simona Ibba, Elena Caloro, Deborah Fazzini, Giancarlo Oliva and Sergio Papa
Digital twins are virtual replicas of physical objects or systems. This new technology is increasingly being adopted in industry to improve the monitoring and efficiency of products and organizations. In healthcare, digital human twins (DHTs) represent v...
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Lefteris Benos, George Ninos, Nickolas D. Polychronopoulos, Maria-Aristea Exomanidou and Ioannis Sarris
Hyperthermia, an alternative medical approach aiming at locally increasing the temperature of a tumor, can cause the ?death? of cancer cells or the sensitization of them to chemotherapeutic drugs and radiation. In contrast with the conventional treatment...
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Mukesh Soni, Tissa Wijeratne and David Ackland
Video and music as a dissociative attention stimulus during exercise is known to distract from the discomfort of physical exertion and improve exercise adherence; however, the influence of video-based feedback and engagement during pedalling on the perfo...
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Joana Morgado, Tania Pereira, Francisco Silva, Cláudia Freitas, Eduardo Negrão, Beatriz Flor de Lima, Miguel Correia da Silva, António J. Madureira, Isabel Ramos, Venceslau Hespanhol, José Luis Costa, António Cunha and Hélder P. Oliveira
The evolution of personalized medicine has changed the therapeutic strategy from classical chemotherapy and radiotherapy to a genetic modification targeted therapy, and although biopsy is the traditional method to genetically characterize lung cancer tum...
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Candace M. Day, Martin J. Sweetman, Yunmei Song, Sally E. Plush and Sanjay Garg
Functionalized nanoparticles have played a major role in the field of targeted therapy, owing to their ability to control the release and for the selective delivery of entrapped materials to tumours. In this work, we described the loading capacity and in...
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Maggie Banys-Paluchowski, Florian Reinhardt and Tanja Fehm
Circulating tumor cells (CTCs) have become one of the key research fields in translational oncology. The molecular characterization of CTCs offers a unique insight into genotypic and phenotypic dynamics of metastatic disease.
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Martyna Trukawka, Krzysztof Cendrowski, Wojciech Konicki and Ewa Mijowska
Herein, we present a facile synthesis route for the mesoporous silica nanoflakes on two types of templates and evaluate their potential as potential drug delivery systems. Silica materials are attractive due to their biocompatibility, low cytotoxicity, h...
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Andrew K.H. Robertson, Andrew Lobbezoo, Louis Moskven, Paul Schaffer and Cornelia Hoehr
With recent impressive clinical results of targeted alpha therapy using 225Ac, significant effort has been directed towards providing a reliable and sufficient supply of 225Ac to enable widespread using of 225Ac-radiopharmaceuticals. TRIUMF has begun pro...
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Daria Kurakina, Mikhail Kirillin, Valeriya Perekatova, Vladimir Plekhanov, Anna Orlova, Ekaterina Sergeeva, Aleksandr Khilov, Anastasiya Nerush, Pavel Subochev, Srivalleesha Mallidi, Ilya Turchin and Tayyaba Hasan
Increase of the efficiency of photodynamic therapy (PDT) requires the development of advanced protocols employing both novel photosensitizer (PS) carriers and aids for online monitoring. Nanoconstructs may be comprised of a photosensitizer, chemotherapy ...
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Romina Mancinelli, Caterina Loredana Mammola, Roberta Sferra, Simona Pompili, Antonella Vetuschi and Luigi Pannarale
Angiogenesis plays a fundamental role in tumor growth and progression. It is regulated by several growth factors, including vascular endothelial growth factor protein family (VEGF) and its receptors, which are probably the most important factors responsi...
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