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Artur Chudzik and Andrzej W. Przybyszewski
Neurodegenerative diseases (NDs), including Parkinson?s and Alzheimer?s disease, pose a significant challenge to global health, and early detection tools are crucial for effective intervention. The adaptation of online screening forms and machine learnin...
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Miranda Bellezza, Azzurra di Palma and Andrea Frosini
Alzheimer?s disease (AD) is a neurodegenerative disorder that leads to the loss of cognitive functions due to the deterioration of brain tissue. Current diagnostic methods are often invasive or costly, limiting their widespread use. Developing non-invasi...
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Hatice Yildirim, Elif Aksöz, Burcu Efe Daskan, Fazilet Sen and Murat Çelebi
This study aimed to investigate the changes in Paraoxonase (PON), Carbonic Anhydrase (CA), and ß-glucosidase levels of different aged rats and scopolamine-induced memory impairment rats. This study used young, adult, and middle-aged male Wistar Albino ra...
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Marianna Capecci, Nicolò Baldini, Francesca Campignoli, Lorenzo Pasquale Lombardo, Elisa Andrenelli and Maria Gabriella Ceravolo
The COVID-19 pandemic has been a stress test for the population, especially for people with chronic disorders such as Parkinson?s disease (PD). In addition to public health restrictions that contrast with PD management recommendations, there were deep ch...
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Pratham Grover, Kunal Chaturvedi, Xing Zi, Amit Saxena, Shiv Prakash, Tony Jan and Mukesh Prasad
Alzheimer?s disease is a chronic neurodegenerative disease that causes brain cells to degenerate, resulting in decreased physical and mental abilities and, in severe cases, permanent memory loss. It is considered as the most common and fatal form of deme...
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Zeyuan Zhao, Ping Li, Yongjie Dai, Zhaoe Min and Lei Chen
Alzheimer?s disease (AD) is an irreversible neurodegenerative disease. Providing trustworthy AD progression predictions for at-risk individuals contributes to early identification of AD patients and holds significant value in discovering effective treatm...
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Zhiqiong Wang, Zican Lin, Shuo Li, Yibo Wang, Weiying Zhong, Xinlei Wang and Junchang Xin
Alzheimer?s disease (AD) is a progressive, irreversible neurodegenerative disorder that requires early diagnosis for timely treatment. Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging technique for detecting brain activity. To ...
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Juan Jiang, Hong Liu, Xin Yu, Jin Zhang, Bing Xiong and Lidan Kuang
Precisely segmenting the hippocampus from the brain is crucial for diagnosing neurodegenerative illnesses such as Alzheimer?s disease, depression, etc. In this research, we propose an enhanced hippocampus segmentation algorithm based on 3D U-Net that can...
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Diletta Piatti, Riccardo Marconi, Giovanni Caprioli, Simone Angeloni, Massimo Ricciutelli, Gokhan Zengin, Filippo Maggi, Luca Pagni and Gianni Sagratini
This study assessed the impact of full and late flowering stages on the polyphenols and enzyme inhibitory properties of Hypericum perforatum from Poland. Recognizing the significance of phenolic compounds in disease prevention and melatonin?s emerging pr...
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Zhaoyi Chen, Yuchen Yang, Dazheng Zhang, Jingchuan Guo, Yi Guo, Xia Hu, Yong Chen and Jiang Bian
Alzheimer?s disease (AD) and AD-related dementias (AD/ADRD) are a group of progressive neurodegenerative diseases. The progression of AD can be conceptualized as a continuum in which patients progress from normal cognition to preclinical AD (i.e., no sym...
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