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Javier Domingo-Espiñeira, Oscar Fraile-Martínez, Cielo Garcia-Montero, María Montero, Andrea Varaona, Francisco J. Lara-Abelenda, Miguel A. Ortega, Melchor Alvarez-Mon and Miguel Angel Alvarez-Mon
Neurological disorders represent the primary cause of disability and the secondary cause of mortality globally. The incidence and prevalence of the most notable neurological disorders are growing rapidly. Considering their social and public perception by...
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Yingcong Huang, Kunal Chaturvedi, Al-Akhir Nayan, Mohammad Hesam Hesamian, Ali Braytee and Mukesh Prasad
Parkinson?s disease (PD) is a chronic brain disorder affecting millions worldwide. It occurs when brain cells that produce dopamine, a chemical controlling movement, die or become damaged. This leads to PD, which causes problems with movement, balance, a...
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Kacey M. Wallace, Michael R. Brown, William C. Pannell, Jacob B. Daniels, Juliana C. Moore, Ayden K. McInnis, Paul T. Donahue and John C. Garner
Single-limb balance training is integral to preventing and rehabilitating lower extremity injuries. Previous investigations have shown that when using instability devices, differences may or may not exist in the postural sway parameters during use, depen...
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Michele Basilicata, Giulia Marrone, Manuela Di Lauro, Eleonora Sargentini, Vincenza Paolino, Redan Hassan, Giuseppe D?Amato, Patrizio Bollero and Annalisa Noce
Gaucher disease (GD) is a lysosomal storage pathological condition, characterized by a genetic autosomal recessive transmission. The GD cause is the mutation of GBA1 gene, located on the chromosome 1 (1q21), that induces the deficiency of the lysosomal e...
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Michal Brzus, Kevin Knoernschild, Jessica C. Sieren and Hans J. Johnson
Translation of basic animal research to find effective methods of diagnosing and treating human neurological disorders requires parallel analysis infrastructures. Small animals such as mice provide exploratory animal disease models. However, many interve...
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Marianna Capecci, Nicolò Baldini, Francesca Campignoli, Lorenzo Pasquale Lombardo, Elisa Andrenelli and Maria Gabriella Ceravolo
The COVID-19 pandemic has been a stress test for the population, especially for people with chronic disorders such as Parkinson?s disease (PD). In addition to public health restrictions that contrast with PD management recommendations, there were deep ch...
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Nikolaos Kladovasilakis, Ioannis Kostavelis, Paschalis Sideridis, Eleni Koltzi, Konstantinos Piliounis, Dimitrios Tzetzis and Dimitrios Tzovaras
During the last decade, soft robotic systems, such as actuators and grippers, have been employed in various commercial applications. Due to the need to integrate robotic mechanisms into devices operating alongside humans, soft robotic systems concentrate...
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M. El Arayshi, C. M. Verrelli, G. Saggio, M. Iosa, A. E. Gentile, L. Chessa, M. Ruggieri and A. Polizzi
Background. It has been shown in the very recent literature that human walking generates rhythmic motor patterns with hidden time harmonic structures that are represented (at the subject?s comfortable speed) by the occurrence of the golden ratio as the t...
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Luciana Rigoli, Valerio Caruso, Concetta Aloi, Alessandro Salina, Mohamad Maghnie, Giuseppe d'Annunzio, Olga Lamacchia, Giuseppina Salzano, Fortunato Lombardo and Giuseppe Picca
Wolfram syndrome 1, a rare autosomal recessive neurodegenerative disease, is caused by mutations in the WFS1 gene. It is characterized by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness (DIDMOAD), and other clinical manifestations such...
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Giannicola Iannella, Giuseppe Magliulo, Antonio Greco, Marco de Vincentiis, Massimo Ralli, Antonino Maniaci, Annalisa Pace and Claudio Vicini
Obstructive sleep apnea (OSA) syndrome is a respiratory sleep disorder characterized by partial or complete recurrent episodes of upper airway collapse that occur during the night. The OSA manifests with a reduction (hypopnea) or complete cessation (apne...
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