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Federica Monaco, Sergio Coluccia, Arturo Cuomo, Davide Nocerino, Daniela Schiavo, Gilda Pasta, Francesca Bifulco, Pasquale Buonanno, Vittorio Riccio, Marianna Leonardi, Francesco Perri, Alessandro Ottaiano, Francesco Sabbatino, Alessandro Vittori and Marco Cascella
Background: Percutaneous electrical nerve stimulation (PENS) is a minimally invasive peripheral neuromodulation approach implemented against chronic neuropathic and mixed pain. This bibliometric study aims to quantitatively evaluate the output of PENS fo...
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Xiaqing Wang, Chongyu Bao, Zhenjiang Li, Lupeng Yue and Li Hu
Humans have used opioids to suppress moderate to severe pain for thousands of years. However, the long-term use of opioids has several adverse effects, such as opioid tolerance, opioid-induced hyperalgesia, and addiction. In addition, the low efficiency ...
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Alessandro de Sire, Antonio Ammendolia, Lorenzo Lippi, Giacomo Farì, Carlo Cisari and Marco Invernizzi
?Mixed pain? is a term recently introduced to define the overlapping of nociceptive, neuropathic and nociplastic pain. To date, it has been reported that pharmacological treatments might have a modest effectiveness on patients affected by mixed chronic p...
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Dragos Paul Mihai, Cosmin Trif, Gheorghe Stancov, Denise Radulescu and George Mihai Nitulescu
Transient receptor potential ankyrin 1 (TRPA1) is a ligand-gated calcium channel activated by cold temperatures and by a plethora of electrophilic environmental irritants (allicin, acrolein, mustard-oil) and endogenously oxidized lipids (15-deoxy-?12, 14...
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Dariusz Kosson, Malgorzata Malec-Milewska, Robert Galazkowski and Patryk Rzonca
The aim of the study was to measure the frequency of such emotional disturbances as anxiety, depression and aggression among patients treated in a pain clinic, as well as assess the factors contributing to such disorders. Research was conducted from Janu...
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