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Isehaq Al-Huseini, Maryam Al-Ismaili, Ammar Boudaka and Srinivasa Rao Sirasanagandla
Vascular calcification is calcium deposition occurring in the wall of blood vessels, leading to mechanical stress and rupture due to a loss of elasticity and the hardening of the vessel wall. The role of the Transient Receptor Channel Vanilloid 4 (TRPV4)...
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Matthew Laffey, Brooke Tornifoglio and Caitríona Lally
Aortic aneurysms (AA) occur in 4.8% of people causing 150,000 deaths annually. While endovascular aneurysm repairs reduce surgical morbidity, device-related failures (leak/displacement) are frequent highlighting the need for test models that better repre...
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Emanuela Bologna, Ettore Dinoto, Francesco Di Simone, Felice Pecoraro, Sara Ragusa, Katia Siciliano and Massimiliano Zingales
Background: The treatment of abdominal aortic aneurysm (AAA) is today commonly treated by inserting a stent-graft by the endovascular route, without resorting to open surgery. However, some clinical cases do not allow this less invasive approach, meaning...
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Ji-Hun You, Chung Won Lee, Up Huh, Chi-Seung Lee and Dongman Ryu
In abdominal aortic aneurysm (AAA), the rupture of the aortic tissue is directly related to wall stress. Thus, the investigation of maximum wall stress is a necessary procedure to predict the aortic rupture in AAA. In this study, computational simulation...
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Nadia Chaher, Reza Hajhosseiny, Alkystis Phinikaridou and René M. Botnar
The extracellular matrix (ECM) is a highly complex macromolecular network present in all tissues and organs. The ECM is continuously remodelling under an orchestrated process facilitated by many matrix-degrading and matrix-synthesising enzymes in both he...
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