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Simone Brogi, Ilaria Guarino, Lorenzo Flori, Hajar Sirous and Vincenzo Calderone
In this study, we applied a computer-based protocol to identify novel antioxidant agents that can reduce oxidative stress (OxS), which is one of the main hallmarks of several disorders, including cancer, cardiovascular disease, and neurodegenerative diso...
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Hokyung Kim, Hayeon Choi, Yoonji Heo, Cheoljae Kim, Min Kim and Ki Tae Kim
Several biological macromolecules adopt bivalent or multivalent interactions to perform various cellular processes. In this regard, the development of molecular constructs presenting multiple ligands in a specific manner is becoming crucial for the under...
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Kazuhiro Nouso, Takamasa Ohki, Tatsuya Yamashita, Haruyuki Takaki, Chien-Au Liu, Tae Wook Kang, Dong Ho Lee, So Jung Lee, Suyash Kulkarni, Deepa Shree and Masatoshi Tanaka
Many guidelines and standard therapies have been published for the treatment of hepatocellular carcinoma (HCC). Multiple options for the treatment of early to intermediate-stage HCC have resulted in several differences between the guidelines. In addition...
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Newton Lo Well
Pág. 1
The modern consumer values convenience, economy, and multifunctionality; these ideas drive and direct the research and development of new and improved laundry detergents. The focus of this research is the development of a methodology for the design of la...
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Mohammed Zaghlool Al-Khayyat
Pág. 1 - 9
Introduction: Chorismate synthase catalyzes the final step in shikimate acid pathway involved in synthesis of aromatic compounds in bacteria. This enzyme can be a possible molecular target for design of antibiotics. Materials and Methods: Homology modeli...
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Sofya V. Lushchekina,Galina F. Makhaeva,Dana A. Novichkova,Irina V. Zueva,Nadezhda V. Kovaleva,Rudy R. Richardson
Pág. 89 - 97
Molecular docking is one of the most popular tools of molecular modeling. However, in certain cases, like development of inhibitors of cholinesterases as therapeutic agents for Alzheimer's disease, there are many aspects, which should be taken into accou...
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José Ariévilo Gurgel Rodrigues, Érico Moura Neto, Lisandra Antônia Castro Teixeira, Regina Célia Monteiro de Paula, Paulo Antônio de Souza Mourão, Norma Maria Barros Benevides
Pág. 611 - 619
Studies on biopolymers from macroalgae suggested sulfated polysaccharides (SPs) as research agents to investigate events related to haemostasis. Caulerpa cupressoides var. lycopodium is a marine green alga containing three SPs fractions (SP1, SP2 and SP3...
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