|
|
|
|
|
Isehaq Al-Huseini, Maryam Al-Ismaili, Ammar Boudaka and Srinivasa Rao Sirasanagandla
Vascular calcification is calcium deposition occurring in the wall of blood vessels, leading to mechanical stress and rupture due to a loss of elasticity and the hardening of the vessel wall. The role of the Transient Receptor Channel Vanilloid 4 (TRPV4)...
ver más
|
|
|
|
|
|
|
|
|
|
|
Alain Nogaret
Model optimization in neuroscience has focused on inferring intracellular parameters from time series observations of the membrane voltage and calcium concentrations. These parameters constitute the fingerprints of ion channel subtypes and may identify i...
ver más
|
|
|
|
|
|
|
|
|
|
|
Dragos Paul Mihai, Cosmin Trif, Gheorghe Stancov, Denise Radulescu and George Mihai Nitulescu
Transient receptor potential ankyrin 1 (TRPA1) is a ligand-gated calcium channel activated by cold temperatures and by a plethora of electrophilic environmental irritants (allicin, acrolein, mustard-oil) and endogenously oxidized lipids (15-deoxy-?12, 14...
ver más
|
|
|
|
|
|
|
|
|
|
|
Patricia P. Wadowski, Georgiana-Aura Giurgea, Oliver Schlager, Anton Luf, Thomas Gremmel, Eva-Luise Hobl, Sylvia Unterhumer, Henriette Löffler-Stastka and Renate Koppensteiner
Objective: N-(2-methoxy) benzyl-phenethylamine (NBOMe) derivatives have a high affinity to the serotonin receptor 2A and emerged as new psychedelic agents. We report the case of a 30-year-old man admitted to the hospital because of acute ischemia of the ...
ver más
|
|
|
|
|
|
|
|
|
|
|
Isis J. Amaye, Thomas Heinbockel, Julia Woods, Zejun Wang, Miguel Martin-Caraballo and Patrice Jackson-Ayotunde
A small library of novel fluorinated N-benzamide enaminones were synthesized and evaluated in a battery of acute preclinical seizure models. Three compounds (GSA 62, TTA 35, and WWB 67) were found to have good anticonvulsant activity in the 6-Hz ‘p...
ver más
|
|
|
|
|
|