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Stefano Alderighi, Paolo Landa, Elena Tànfani and Angela Testi
Molecular genetic techniques allow for the diagnosing of hereditary diseases and congenital abnormalities prenatally. A high variability of treatments exists, engendering an inappropriate clinical response, an inefficient use of resources, and the violat...
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Teresa Gonçalves, Rute Veladas, Hua Yang, Renata Vieira, Paulo Quaresma, Paulo Infante, Cátia Sousa Pinto, João Oliveira, Maria Cortes Ferreira, Jéssica Morais, Ana Raquel Pereira, Nuno Fernandes and Carolina Gonçalves
This paper presents an analysis of the calls made to the Portuguese National Health Contact Center (SNS24) during a three years period. The final goal was to develop a system to help nurse attendants select the appropriate clinical pathway (from 59 optio...
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Se Yun Jeong, Kwang Ho Lee, Jae Kwan Kim, Dohee Ahn, Hyemin Kim, Sang J. Chung, Sun-Young Yoon and Ki Hyun Kim
Ginkgo biloba L. (Ginkgoacea) contains an abundance of beneficial compounds and has demonstrated positive clinical effects in the management of metabolic syndrome. Recent studies have emphasized its efficacy against type 2 diabetes mellitus (T2DM), inclu...
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Antonio Romano, Federica Di Spirito, Alessandra Amato, Giuseppe Andrea Ferraro, Gianna Dipalma, Edit Xhajanka, Rosario Serpico, Francesco Inchingolo and Maria Contaldo
The innovative perspectives of the modern medical era aim to reach the highest performance and accuracy of therapeutic processes carried out for the evolution of diagnostic pathways. Digital planning and real-time diagnosis represent the hottest topics f...
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Deniz Can Guven, Taha Koray Sahin, Alessandro Rizzo, Angela Dalia Ricci, Sercan Aksoy and Kazim Sahin
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and reshaped medical oncology practice over the past decade. However, despite unprecedented and durable clinical responses, most patients eventually fail to respond to ICI therapy due...
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Xingyu Li, Amit Madhukar Kudke, Felix Joseph Nepveux V and Yan Xu
This network-based pharmacology study intends to uncover the underlying mechanisms of cannabis leading to a therapeutic benefit and the pathogenesis for a wide range of diseases claimed to benefit from or be caused by the use of the cannabis plant. Canna...
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Jyoti R. Munavalli, Shyam Vasudeva Rao, Aravind Srinivasan and Frits Van Merode
Evolutionary algorithms, such as genetic algorithms have been used in various optimization problems. In this paper, we propose to apply this algorithm to obtain the layout design/redesign in order to improve the patient flow in an outpatient clinic. Layo...
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Valentina Marassi, Stefano Giordani, Pierluigi Reschiglian, Barbara Roda and Andrea Zattoni
The interaction of heme with blood serum proteins plays an important role in many physiological and pathological processes involving enzyme activity, gene expression and cell proliferation. The mechanisms underlying these interactions are; however, not y...
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Lars Boeckmann, Mirijam Schäfer, Thoralf Bernhardt, Marie Luise Semmler, Ole Jung, Gregor Ojak, Tobias Fischer, Kirsten Peters, Barbara Nebe, Brigitte Müller-Hilke, Christian Seebauer, Sander Bekeschus and Steffen Emmert
Plasma medicine is gaining increasing attention and is moving from basic research into clinical practice. While areas of application are diverse, much research has been conducted assessing the use of cold atmospheric pressure plasma (CAP) in wound healin...
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Zahraa Al Bander, Marloes Dekker Nitert, Aya Mousa and Negar Naderpoor
The gut microbiota encompasses a diverse community of bacteria that carry out various functions influencing the overall health of the host. These comprise nutrient metabolism, immune system regulation and natural defence against infection. The presence o...
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