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Cosimo Cardellicchio, Valentino Laquintana, Rosa Maria Iacobazzi, Nunzio Denora, Antonio Scilimati, Maria Grazia Perrone and Maria Annunziata M. Capozzi
Sulindac is a well-known anti-inflammatory agent, sometimes employed as an adjuvant in antitumor therapy. Due to the recent interest in sulfoximine for its potential chemotherapeutics, we decided to transform sulindac and its methyl ester into the corres...
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En-Shyh Lin and Cheng-Yang Huang
Plinia cauliflora has been associated with numerous ethnobotanical applications. In this study, we uncovered that the fruit extract of P. cauliflora, obtained using 50% ethanol, possesses inhibition activity against the Klebsiella pneumoniae single-stran...
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Gloria Perazzoli, Carolina de los Reyes, Cristina Pinedo-Rivilla, Rosa Durán-Patrón, Josefina Aleu, Laura Cabeza, Consolación Melguizo and Jose Prados
The marine environment is a promising source of natural products with possible pharmacological applications. In this sense, marine microorganisms, especially marine fungi, can produce bioactive compounds with various therapeutic properties. Colorectal ca...
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Jinfeng Yang, Yong Soo Kwon, Eun Soo Seong and Myong Jo Kim
Dendrobium loddigesii has long been used in traditional folk medicine. The purpose of this study was to optimize the culture conditions for its protocorm-like bodies (PLBs) and explore their biological activities. The use of an air-lift bioreactor demons...
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Agnieszka Lubek-Nguyen, Marta Olech, Natalia Nowacka-Jechalke, Aleksandra Martyna, Konrad Kubinski, Maciej Maslyk, Marcin Moczulski and Sebastian Kanak
Crude polysaccharide fraction from Rosa rugosa Thunb. root may constitute a potential functional component, e.g., for the pharmaceutical or cosmetic industry.
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Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Carmela Saturnino, Maria Grazia Bonomo, Carlo Franchini and Maria Stefania Sinicropi
Schiff bases, named after Hugo Schiff, are highly reactive organic compounds broadly used as pigments and dyes, catalysts, intermediates in organic synthesis, and polymer stabilizers. Lots of Schiff bases are described in the literature for various biolo...
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Anna Caruso, Alexia Barbarossa, Alessia Carocci, Giovanni Salzano, Maria Stefania Sinicropi and Carmela Saturnino
The carbazole class is made up of heterocyclically structured compounds first isolated from coal tar. Their structural motif is preponderant in different synthetic materials and naturally occurring alkaloids extracted from the taxonomically related highe...
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Maria Michela Salvatore, Vincenza De Gregorio, Monica Gallo, Maria Michela Corsaro, Angela Casillo, Raffaele Vecchione, Anna Andolfi, Daniele Naviglio and Paolo Antonio Netti
In this study two extraction methods for Ganoderma lucidum spores were evaluated for the potential use of extracted compounds in cancer treatments. Our findings showed that the innovative Rapid Solid Liquid Dynamic Extraction (RSLDE) permits the successf...
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Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Fardous F. El-Senduny, Farid A. Badria, A. F. M. Motiur Rahman, Assem Barakat and Yaseen A. M. M. Elshaier
A one-pot, single-step, and an atom-economical process towards the synthesis of highly functionalized spirooxindoles analogues was efficiently conducted to produce a satisfactory chemical yields (70?93%) with excellent relative diastereo-, and regio-sele...
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Sumangala Darsandhari, Biplav Shrestha, Ramesh Prasad Pandey, Sanghun Lee, Hye Jin Jung, Yeon Ju Kim and Jae Kyung Sohng
A glycoside derivative of compound K (CK) was synthesized by using a glycosyltransferase, and its biological activity was tested against various cancer-cell lines. A regiospecific, ß-1,4-galactosyltransferase (LgtB) converted 100% of 0.5 mmol CK into a g...
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