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Rocco A. Scollo, Antonio G. Spampinato, Georgia Fargetta, Vincenzo Cutello and Mario Pavone
Disease phenotypes are generally caused by the failure of gene modules which often have similar biological roles. Through the study of biological networks, it is possible to identify the intrinsic structure of molecular interactions in order to identify ...
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José Pinto, João R. C. Ramos, Rafael S. Costa and Rui Oliveira
In this paper, a computational framework is proposed that merges mechanistic modeling with deep neural networks obeying the Systems Biology Markup Language (SBML) standard. Over the last 20 years, the systems biology community has developed a large numbe...
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Yijun Xiao, Hui Lv and Xing?an Wang
The emerging field at the intersection of synthetic biology, network modelling, and control theory has grown in popularity in recent years. In this study, the aim is to design synthetic biomolecular controllers by exploiting the covalent modification cyc...
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Hyungsik Shin, Jeryang Park and Dongwoo Kang
Networks can be used to model various aspects of our lives as well as relations among many real-world entities and objects. To detect a community structure in a network can enhance our understanding of the characteristics, properties, and inner workings ...
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Baihan Lin
The absence of a conventional association between the cell?cell cohabitation and its emergent dynamics into cliques during development has hindered our understanding of how cell populations proliferate, differentiate, and compete (i.e., the cell ecology)...
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Manon Ruffini, Jelena Vucinic, Simon de Givry, George Katsirelos, Sophie Barbe and Thomas Schiex
Proteins are the main active molecules of life. Although natural proteins play many roles, as enzymes or antibodies for example, there is a need to go beyond the repertoire of natural proteins to produce engineered proteins that precisely meet applicatio...
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Tian Lan, Qian Peng, Haoyu Wang, Xinyu Gong, Jing Li and Zhicheng Shi
Allometric scaling originates in biology, where it refers to scaling relations between the size of a body part and the size of the whole body when an organism grows. In cities, various allometric relations have also been discovered, such as those between...
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Péter Marjai, Bence Szabari and Attila Kiss
Graphs can be found in almost every part of modern life: social networks, road networks, biology, and so on. Finding the most important node is a vital issue. Up to this date, numerous centrality measures were proposed to address this problem; however, e...
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Pavel Gotovtsev
There are a number of significant changes taking place in modern city development and most of them are based on the number of recent technological progress. This paper provides a review and analysis of recent approaches of biotechnology that can find a p...
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Alessio Martino, Alessandro Giuliani and Antonello Rizzi
This paper investigates a novel graph embedding procedure based on simplicial complexes. Inherited from algebraic topology, simplicial complexes are collections of increasing-order simplices (e.g., points, lines, triangles, tetrahedrons) which can be int...
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