Resumen
The current study is an attempt to explore the host?bacterial interaction of periodontal pathogens in the oral environment under experimental conditions that may be influenced by areca nut extracts. The function of neutrophils differs in peripheral blood and gingival crevicular fluid. This study observed a reduction in the bactericidal activity of crevicular polymorphonuclear neutrophils isolated from chronic periodontitis patients and healthy subjects in the presence of areca nut extracts. This could be one of the mechanisms by which the areca nut compromises periodontal health.