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Inicio  /  Instruments  /  Vol: 6 Par: 4 (2022)  /  Artículo
ARTÍCULO
TITULO

A Thermal Sublimation Generator of 131mXe

Karolina Kulesz    
Nikolay Azaryan    
Mikolaj Baranowski    
Mateusz Jerzy Chojnacki    
Ulli Köster    
Razvan Lica    
Sorin Gabriel Pascu    
Renaud Blaise Jolivet and Magdalena Kowalska    

Resumen

Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133 133 Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131m 131 m Xe. This production method utilized the decay of 131 131 I, obtained commercially from a hospital supplier in the form of Na131 131 I powder. Heat treatments of the Na131 131 I powder and cryogenic trapping of released 131m 131 m Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131m 131 m Xe and 131 131 Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131m 131 m Xe for small-scale experiments.

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