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Bárbara Costa, Rita Matos, Irina Amorim, Fátima Gärtner and Nuno Vale
The breast cancer therapies available are insufficient, especially since first-line treatments, such as paclitaxel, result in drug resistance and their toxicity often limits their concentration. Strategies like drug repurposing are beneficial, and novel ...
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Kanoknate M. Supasri, Manoj Kumar, Anna Segecová, Janice I. McCauley, Andrei Herdean, Matthew P. Padula, Tim O?Meara and Peter J. Ralph
Peridinin-Chlorophyll a-Proteins (PCP) are the major light harvesting proteins in photosynthetic dinoflagellates. PCP shows great variation in protein length, pigment ratio, sequence, and spectroscopic properties. PCP conjugates (PerCP) are widely used a...
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Maggie Banys-Paluchowski, Florian Reinhardt and Tanja Fehm
Circulating tumor cells (CTCs) have become one of the key research fields in translational oncology. The molecular characterization of CTCs offers a unique insight into genotypic and phenotypic dynamics of metastatic disease.
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Claudio Luparello, Debora Ragona, Dalia Maria Lucia Asaro, Valentina Lazzara, Federica Affranchi, Vincenzo Arizza and Mirella Vazzana
Triple-negative breast cancer (TNBC) is a highly malignant tumor histotype which lacks effective targeted therapies, thereby being considered as the most aggressive form of breast carcinoma. To identify novel compounds which could counteract TNBC cell gr...
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Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Fardous F. El-Senduny, Farid A. Badria, A. F. M. Motiur Rahman, Assem Barakat and Yaseen A. M. M. Elshaier
A one-pot, single-step, and an atom-economical process towards the synthesis of highly functionalized spirooxindoles analogues was efficiently conducted to produce a satisfactory chemical yields (70?93%) with excellent relative diastereo-, and regio-sele...
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