Redirigiendo al acceso original de articulo en 15 segundos...
Inicio  /  Algorithms  /  Vol: 17 Par: 2 (2024)  /  Artículo
ARTÍCULO
TITULO

Assessing the Impact of Patient Characteristics on Genetic Clinical Pathways: A Regression Approach

Stefano Alderighi    
Paolo Landa    
Elena Tànfani and Angela Testi    

Resumen

Molecular genetic techniques allow for the diagnosing of hereditary diseases and congenital abnormalities prenatally. A high variability of treatments exists, engendering an inappropriate clinical response, an inefficient use of resources, and the violation of the principle of the equality of treatment for equal needs. The proposed framework is based on modeling clinical pathways that contribute to identifying major causes of variability in treatments justified by the clinical needs? variability as well as depending on individual characteristics. An electronic data collection method for high-risk pregnant women addressing genetic facilities and laboratories was implemented. The collected data were analyzed retrospectively with two aims. The first is to identify how the whole activity of genetic services can be broken down into different clinical pathways. This was performed by building a flow chart with the help of doctors. The second aim consists of measuring the variability, within and among, the different paths due to individual characteristics. A set of statistical models was developed to determine the impact of the patient characteristics on the clinical pathway and its length. The results show the importance of considering these characteristics together with the clinical information to define the care pathway and the use of resources.

 Artículos similares

       
 
Sean Pascoe    
Data envelopment analysis (DEA) has been proposed as a means of assessing alternative management options when there are multiple criteria with multiple indicators each. While the method has been widely applied, the implications of how the method is appli... ver más
Revista: Algorithms

 
Jiangtao Chen, Jiao Zhao, Wei Xiao, Luogeng Lv, Wei Zhao and Xiaojun Wu    
Given the randomness inherent in fluid dynamics problems and limitations in human cognition, Computational Fluid Dynamics (CFD) modeling and simulation are afflicted with non-negligible uncertainties, casting doubts on the credibility of CFD. Scientifica... ver más
Revista: Aerospace

 
Yan Zhang, Bingfei Chu, Tianming Huang, Shengwen Qi, Michael Manga, Huai Zhang, Bowen Zheng and Yuxin Zhou    
Carbon geological storage (CGS) is an important global practice implemented to mitigate the effects of CO2 emissions on temperature, climate, sea level, and biodiversity. The monitoring of CGS leakage and the impact of storage on hydrogeological properti... ver más
Revista: Water

 
Juan M. Soria, Juan Víctor Molner, Rebeca Pérez-González, Bárbara Alvado, Lucía Vera-Herrera and Susana Romo    
The Albufera of Valencia, a Mediterranean coastal lagoon, has been in a turbid state since 1974, with only four episodes of temporary water transparency in spring. Despite its average depth of 1 m and oligohaline waters, excessive turbidity, fish grazing... ver más

 
?tefan Bila?co and Titus-Cristian Man    
On a global scale, traffic incidents are a leading cause of mortality and material damage. Romania exhibits the highest rate of road traffic fatalities both in the European Union and worldwide, requiring a comprehensive examination of its overall influen... ver más
Revista: Applied Sciences